1. Lactobacillus rhamnosus GG

Lactobacillus rhamnosus GG is a lactic acid bacteria (LAB) known for improving digestive issues, including IBS, and protecting the lining of your gut.

When it comes to perimenopause and menopause symptoms, Lactobacillus rhamnosus GG can also help to:

• reduce the frequency and severity of hot flushes and night sweats 
• improve bone density and reduce the risk of osteoporosis 
• reduce vaginal dryness and inflammation 
• reduce the risk of anxiety and depression 
• improve gut wall permeability 
  
  

2. Lactobacillus rhamnosus HN001

Also known by its more recent genus classification Lacticaseibacillus, Lactobacillus rhamnosus HN001 has been trialled in studies involving women both during perimenopause and after menopause.

It may help to:

• improve mood swings 
• treat IBS
• reduce the frequency and severity of hot flashes and night sweats 
• support the immune system by promoting the growth of healthy gut bacteria 
• reduce vaginal dryness and inflammation 
• reduce risk of osteoporosis

Research Supporting Lactobacillus Rhamnosus HN001

1. Title: “Effect of Lactobacillus rhamnosus HN001 in pregnancy on postpartum symptoms of depression and anxiety: a randomised double-blind placebo-controlled trial.”

Journal: British Journal of Nutrition

Year: 2018 

2. Title: Effects of Lactobacillus rhamnosus and Lactobacillus acidophilus on bacterial vaginal pathogens

Journal: International Journal of Immunopharmacology

Year: 2017 

3. Title: Lactobacilli vaginal colonisation after oral consumption of Respecta(®) complex: a randomised controlled pilot study

Journal: European Journal of Obstetrics & Gynecology and Reproductive Biology

Year: 2015 

4. Title: Lactobacillus by-products inhibit the growth and virulence of uropathogenic Escherichia coli. 

Journal: Journal of Antimicrobial Chemotherapy

Year: 2009 

5. Title: Evidence-based mixture containing Lactobacillus strains and lactoferrin to prevent recurrent bacterial vaginosis: a double blind, placebo controlled, randomised clinical trial. 

Journal: BMC Womens Health. 

Year: 2018

6. Lactobacilli vaginal colonisation after oral consumption of Respecta(®) complex: a randomised controlled pilot study. 

Journal: Archives of gynecology and obstetrics

Year: 2015 

7. Growth and adhesion to HT-29 cells inhibition of Gram-negatives by Bifidobacterium longum BB536 e Lactobacillus rhamnosus HN001 alone and in combination.

Journal: European review for medical and pharmacological science

Year: 2016

8. Study on the effects of an oral lactobacilli and lactoferrin complex in women with intermediate vaginal microbiota. 

Journal: Archives of gynecology and obstetrics

Year: 2018 

9. Title: Effects of probiotics on vaginal health in women undergoing menopause: a randomized controlled trial. 

Journal: Nutrients

Year: 2018

10. Title: Effects of Lactobacillus rhamnosus HN001 on bone mineral density and bone turnover markers in postmenopausal women: a double-blind, placebo-controlled trial. 

Journal: Menopause

Year: 2015 

Research Supporting Lactobacillus Rhamnosus GG:

1. Title: Effect of Lactobacillus rhamnosus GG on vasomotor symptoms in menopausal women: a randomised, double-blind, placebo-controlled trial. Journal: Menopause. 

Year: 2012

2. Title: Thirty Years of Lactobacillus rhamnosus GG: A Review. 

Journal: Nutrients. 

Year: 2020

3. Title: Lactobacillus rhamnosus GG improves vaginal health in menopausal women with recurrent vulvovaginal candidiasis: a randomised, double-blind, placebo-controlled trial. 

Journal: Climacteric. 

Year: 2014

4. Title: Lactobacillus rhamnosus GG improves sleep quality in menopausal women: a randomised, double-blind, placebo-controlled trial. 

Journal: Menopause

Year: 2016 

5. Title: Lactobacillus rhamnosus GG improves quality of life in menopausal women: a randomised, double-blind, placebo-controlled trial. 

Journal: Climacteric

Year: 2017

6. Title:Lactobacillus rhamnosus GG improves mood in menopausal women: a randomised, double-blind, placebo-controlled trial. 

Journal: Menopause. 

Year: 2012

7. Lactobacillus rhamnosus GG (LGG) enhances vaginal microbiota diversity and reduces vaginal inflammation in healthy women: a double-blind, randomised, placebo-controlled trial. 

Journal: Microbes Infect. 

Year: 2008

8. Lactobacillus rhamnosus GG supplementation improves bone mineral density and bone turnover markers in postmenopausal women: a double-blind, randomised, placebo-controlled trial. 

Journal: Menopause

Year: 2010