• Joanna Lyall

    CEO & Founder of The Better Menopause, Nutritional Therapist (Dip Nut, mBANT, CNHC)

    In 2006, Jo certified as a nutritional therapist and set up her own private practice specialising in women’s health and hormones. With well over two decades of experience, Jo is a firm believer in the transformative power of nutrition, wellness and complementary health. Drawing on her previous career as a leader and CEO in the media industry, Jo witnessed firsthand the impact of investing in one’s health on performance and happiness.

  • Dr Shahzadi Harper

    Resident Doctor at The Better Menopause.

    Certified in Menopause Management, Functional Medicine, Member of the British Menopause Society, European Andropause and Menopause Society and Primary Care Society of Gastroenterology. 

    After 5 years of running her specialist clinic, Dr Harper has a deep understanding of the symptoms & concerns women face at this critical life stage. She believes in the early management of symptoms of perimenopause and menopause to maintain your health & confidence. 

1 of 2
  • Lactobacillus rhamnosus

    The Better Gut contains 2 different strains of this Bacteria.

    To improve resilience to stress & anxiety*

    Helps to reduce vaginal dryness, inflammation & bloating*

    No. of studies: 19

    Year of studies: 2008-2022

  • Bifidobacterium lactis

    To reduce hot flushes and night sweats*

    No. of studies: 5

    Year of studies: 2008-2017

  • Lactobacillus reuteri

    To improve mood & sleep quality*

    No. of Studies: 5

    Year of studies: 2005-2022

  • Bifidobacterium bifidum

    To improve bowel regularity & constipation*

    No. of Studies: 5

    Year of studies: 2010-2017

  • Lactobacillus acidophilus

    To prevent vaginal and urinary tract infections *

    No. of studies: 5

    Year of studies: 2005-2022

1 of 5

What is the gut-hormone connection? 

Research indicates that the gut-hormone axis may influence the activity of oestrogen and the amount that the amount that a woman has circulating in her body At the centre of this relationship is the estrobolome. 

The estrobolome is a collection of bacteria in the gut microbiome that appears to play a role in metabolising (processing) oestrogen. The term combines "estro", relating to “estrogen”, and "bolome", which refers to the complete set of genes or genetic material of a specific group of organisms.

During a woman’s monthly cycle, oestrogen cycles up and down. Higher levels of oestrogen help our gut enzymes to work efficiently to support our digestive health. But when we transition into perimenopause, our oestrogen levels peak and trough. Therefore, the production of these enzymes is reduced, causing disruption to the bacteria in the estrobolome. 

This shift in the composition of bacteria can be directly linked to common menopause symptoms such as increased incidence of IBS, bloating, hot flushes, weight gain, anxiety, brain fog, low energy, mood swings and more. Of particular interest is the link between symptoms such as vaginal pain, dryness and urinary tract infections, and the types of bacteria that cause these. 

Research suggests that by promoting the growth of beneficial bacteria and supporting a healthy estrobolome, we may be able to significantly alleviate symptoms of perimenopause and menopause. 

It's important to note that while the estrobolome shows promise in scientific research, more studies are needed to fully understand its mechanisms, establish causal relationships, and develop practical applications. Nonetheless, the exploration of the estrobolome highlights the intricate connection between our gut microbiota and hormonal health, opening up exciting possibilities for personalised approaches to support optimal oestrogen metabolism and overall wellbeing.